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氯吡格雷结合氟砍他汀治水疗脑梗死的临床效实

发布时间:2018-10-06 03:52编辑:admin阅读(

      氯吡格雷结合氟砍他汀治水疗脑堵塞塞临床剖析

      李瑞珍

      [摘要] 目的 不清雅察氯吡格雷结合氟砍他汀治水疗脑梗死的临床效实。 方法 拔取本院2013年1月~2014年6月顶出产院的脑梗死患者61例,采取365体育备用法分为对照组(31例)和治水疗组(30例),对照组赋予抗血小板、投降血压、胰岛斋把持血糖等揪容例治水疗;治水疗组在揪容例治水疗的基础上加以用氯吡格雷75 mg,1次/d内服,氟砍他汀40 mg,深睡前内服。1周为1个疗程,治水疗两个疗程。治水疗后,比较治水疗前后两组患者的C-反应蛋清、血脂变募化情景及临床疗效。 结实 治水疗后,治水疗组的C-反应蛋清、TC及LDL-C程度分低于对照组,差异拥有统计学意思(P<0.05);治水疗组尽拥有效力为93.33%,高于对照组的83.87%,差异拥有统计学意思(P<0.05)。 定论 氯吡格雷结合氟砍他汀治水疗脑梗死能清楚改革患者病情,效实清楚,犯得着临床铰行运用。

      [365体育备用] 脑梗死;氯吡格雷;氟砍他汀

      [中图分类号] R971 [文件标注识码] A [文字编号] 1674-4721(2015)02(a)-0085-03

      Clinical efficacy observation of clopidogrel combined with fluvastatin in treatment of cerebral infarction

      LI Rui-bao

      Department of Pharmacy,the Central Hospital of Jiangmen City in Guangdong Province,Jiangmen 529000,China

      [Abstract] Objective To observe the clinical efficacy of clopidogrel combined with fluvastatin in treatment of cerebral infarction. Methods 61 cases of patients with cerebral infarction treated in our hospital from January 2013 to June 2014 were selected,and were randomly divided into control group (31 cases) and treatment group (30 cases).The control group were taken with antiplatelet,lowering blood pressure,insulin to control blood sugar and other conventional treatment,on the basis of conventional treatment,the treatment group were taken with clopidogrel 75 mg oral,once a day;fluvastatin 40 mg,before sleep,oral.One week as a course,two courses of treatment. C-reactive protein,blood lipid changes and clinical efficacy of the two groups was compared. Results After treatment,C-reactive protein,TC and LDL-C of treatment group was lower than that of control group,the difference was significant (P<0.05).The total effective rate of treatment group was 93.33%,higher than 83.87% of the control group,the difference was significant (P<0.05). Conclusion Clopidogrel combined with fluvastatin in treatment of cerebral infarction can significantly improve the patients′ condition,the efficacy is significant,and is worthy of clinical promotion.

      [Key words] Cerebral infarction;Clopidogrel;Fluvastatin

      脑梗死是鉴于脑触动脉主干或皮质触动脉顶干触动脉粥样坚硬募化,致血管内皮斑块堆增厚、管腔小小合塞,使血管内血活触动力学改触动,并终极招致血栓栓塞脑触动脉[1],却惹宗片断脑布匹局血流动灌溉增添以或供血阻断,脑细胞及四周布匹局缺乏血氧供应而突发变质死并产生局灶性神物经体系症状。缺血性脑梗死是最微少见的脑血管疾病,其高栓塞比值、高致残比值及较差的预后均给患者形成不成叛逆转的后遗症,严重为害患者的体强大健与生活品质。当前抗血栓疗法临床效实并不雄心,为了违反掉落雄心疗效及较高的预后效实,对脑梗死患者尽早、正确地运用药物到关要紧。临床切磋发皓,氯吡格雷能拥有效按捺血小板在血管内皮的聚集儿子,氟砍他汀却很好地把持血脂、投降低血黏稠糊度[2]。本切磋经度过不清雅察用药前后C-反应蛋清程度、血脂改触动情景及临床症状改革情景,讨论氯吡格雷及氟砍他汀对脑梗死患者的临床疗效。